Jessica Pearce

MBBS (2014), PGCert Health Professionals Education (2016), PGCert Health Research (2020), MRCP (2020)

Medical Oncology Registrar and NIHR Doctoral Research Fellow

Email: j.pearce@leeds.ac.uk

Jess is a Medical Oncology Registrar, and is currently Out Of Programme completing an NIHR-funded Doctoral Research Fellowship. Jess’s PhD involves leading the FRAME study (frailty-informed cancer management; https://fundingawards.nihr.ac.uk/award/NIHR302560) which looks at integrating frailty assessment within specialist cancer services to support shared treatment decision-making for those with advanced cancer. Jess commenced her PhD in October 2022 and is supervised by Dr Alex Gilbert and Prof Galina Velikova from the Patient-Centered Outcomes Research (PCOR) group, as well as Prof Suzanne Richards and Prof Andrew) Clegg.

Jess graduated from Hull York Medical School in 2014, and followed a seamless track of NIHR-funded clinical academic training prior to starting her PhD. She undertook the Academic Foundation Programme in Medical Education (Hull York Medical School, 2016), at which time she completed a PGCert in Health Professionals Education and gained fellowship of the higher education academy. She them commenced an Academic Clinical Fellowship in Medical Oncology, during which she joined the PCOR group and also completed a PGCert in Health Research (University of Leeds, 2020).

Research Interests

Jess’ research interests include:

  • Geriatric oncology and optimising cancer care and research for older adults and people living with frailty
  • Assessment of frailty in routine cancer care
  • Use of frailty assessments to support treatment decision-making

Papers since joining the PCOR group:

Pearce J, Martin S, Heritage S, Khoury EG, Kucharczak J, Nuamek T, Cairns DA, Velikova G, Richards SH, Clegg A, Gilbert A, Frailty and outcomes in adults undergoing systemic anticancer treatment: a systematic review and meta-analysis, JNCI: Journal of the National Cancer Institute, 2025;, djaf017 https://doi.org/10.1093/jnci/djaf017

Gilbert A, Rostoft S, Vendrely V, Muirhead R, Pearce J, Lievre A, Guren MG. Treatment of anal cancer in older patients and patients with frailty. ESMO Gastrointestinal Oncology. In press 2025 Mar;:100155

Gomes F, Farrington N, Pearce J, Swinson D, Welford J, Greystoke A, Baxter M, Brown-Kerr AG, Wyld L, Morgan J, Battisti NML, Barrell A, Cobben D, Cree A, Johnston M, Colquhoun K, Phillips I, Smith J, Stapley S, Lyons L, Balachandran K, Brown H, Bryce R, Dacie R, Parks R, Denholm M, Harari D, Rigden T, Sommer D, Williams K, Worby K, Cheung KL. The care of older patients with cancer across the United Kingdom in 2024: a narrative review by the International Society of Geriatric Oncology (SIOG) UK Country Group. Journal of Geriatric Oncology. 2025 Jan; 16(1):102133 https://doi.org/10.1016/j.jgo.2024.102133

Rao AR, Noronha V, Ramaswamy A, Kumar A, Pillai A, Gattani S, Sehgal A, Kumar S, Castelino R, Pearce J, Dhekale R, Jagtap P, Tripathi V, Satamkar S, Krishnamurthy J, Mahajan S, Daptardar A, Sonkusare L, Deodhar J, Ansari N, Vagal M, Mahajan P, Timmanpyati S, Nookala M, Chitre A, Kapoor A, Gota V, Banavali S, Badwe RA, Prabhash K. Assessing Frailty in Oncology: Comparative Analysis of Three Scales and Their Implications for Mortality. Journal of Geriatric Oncology. 2024 Apr;15(3):101736 https://doi.org/10.1016/j.jgo.2024.101736

The Joint Collegiate Council for Oncology. Implementing frailty assessment and management in oncology services. London: The Royal College of Radiologists, 2023. Available from: https://www.rcr.ac.uk/our-services/all-our-publications/clinical-oncology-publications/implementing-frailty-assessment-and-management-in-oncology-services/

Spencer K, Absolom KL, Allsop MJ, Relton SD, Pearce J, Liao K, Naseer S, Salako O, Howdon D, Hewison J, Velikova G, Faivre-Finn C, Bekker HL, van der Veer SN. Fixing the leaky pipe: how to improve the uptake of patient reported outcomes-based prognostic and predictive models in cancer clinical practice. JCO Clin Can Inform. 2023 Sep;7:e2300070 https://doi.org/10.1200/cci.23.00070

Khoury EG, Nuamek T, Heritage S, Fulton-Ward T, Kucharczak J, Ng C, Kalsi T, Gomes F, Lind MJ, Battisti NML, Cheung KL, Parks R, Pearce J, and Baxter MA. Geriatric Oncology as an Unmet Workforce Training Need in the United Kingdom—A Narrative Review by the British Oncology Network for Undergraduate Societies (BONUS) and the International Society of Geriatric Oncology (SIOG) UK Country Group. Cancers. 2023 Sept;15(19):4782. https://doi.org/10.3390/cancers15194782

Pearce J, Swinson D, Cairns D, Nair S, Baxter M, Petty R, Seymour M, Hall P, Velikova G, GO2 trial investigators. Frailty and treatment outcome in advanced gastro-oesophageal cancer: an exploratory analysis of the GO2 trial. Journal of Geriatric Oncology. 2022 Apr;13(3):287-293. https://www.ncbi.nlm.nih.gov/pubmed/34955446