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Project title: Curative treatment modalities of early stages Non-Small Cell Lung Cancer: Effect on Patient Reported Outcomes of Video Assisted Thoracoscopic (VATS) Resection and Stereotactic Ablative Body Radiotherapy (SABR)

Project start date: April 2016

Anticipated end date: March 2019

Funding: Yorkshire Cancer Research


Lung cancer is the most common cancer in Yorkshire, with around 4,500 people diagnosed with the disease every year. Videoassisted thoracoscopic surgery (key-hole) is becoming the standard of care for stages I-II Non-small cell lung cancer (NSCLC). Stereotactic Ablative Body Radiotherapy is an accepted alternative for medically inoperable patients. Patient preferences influencing the decision to proceed to one of these treatments have not been investigated.

Aims and objectives

This is a prospective longitudinal observational study to monitor the effects on Patients Reported Outcomes (PROMs) of VATS lung resections and SABR delivered at Leeds Cancer Center for early stages of NSCLC patients. In particular it will inform recruitment and attrition rates and adherence to PROMs reporting during the study, exploring implementation issues through patient and staff interview.

Information about PROMs on the different treatment options may support future Yorkshire patients to make informed treatment decision after diagnosis of NSCLC. The data may help clinicians during the discussion of treatment choices and improve patient-doctor communication.


This project aims to depict the trajectory of two lung cancer treatments from the patient point of view: the key-hole approach and the Stereotattic Ablative Body Radiation Therapy (SABRT).

With the help of an existing electronic patient portal in Leeds for self-reporting of symptoms or adverse treatment effects, we will:

  • Detect changes in daily quality of life before and through all the first year after treatments.
  • Better understand how patient has been involved in making an informed choice before treatment.
  • Find any correlation between clinical history and changes in Quality of Life after lung cancer treatments.

Lead applicant: Professor Galina Velikova


  • Cecilia Pompili
  • Trish Holch
  • Kevin Franks (Clin Oncology)
  • Matthew Callister (Resp Medicine)
  • Johnathan Robson (Resp Medicine)

For further information about this project please contact Dr Cecilia Pompili: c.pompili@leeds.ac.uk