Dr Trish Holch

Dr Trish Holch

PhD Psychology (2009), BSc (Hons) Applied Psychology (2003), RGN (1993)

Research Fellow

Email: t.holch@leeds.ac.uk

Trish joined the Patient Reported Outcomes Group in 2009 and now holds an honorary contract with the University of Leeds. Her background is in Psychology specifically Behavioural Neuroscience. She completed a PhD (2009) from the Institute of Psychological Sciences at the University of Leeds where she explored ‘the inconsistent effects of the neuropeptide PYY3-36 on appetite’. Trish attained a BSc (Hons) degree in Applied Psychology from the same institution (2003) and as a postgraduate she was a keen member of the Biopsychology Research Group. Following her husband’s diagnosis of terminal prostate cancer Trish changed the focus of her career to the psychosocial needs of oncology patients where she has been able to utilize both her psychological knowledge and former clinical experience as a nurse.

She is one of the co-applicants supporting the Radiotherapy strand of the multi-centre National Institute of Health Research (NIHR)-funded eRAPID programme grant (Leeds and Christie Hospital Manchester). Previously she led a work stream in the NIHR-funded development grant (eRAPID) reviewing and developing items suitable for patients to self-report adverse events (AE) and developing patient and clinical toxicity management advice.

Research Interests

Trish’s interests include symptom/adverse event/toxicity monitoring and assessment of quality of life (QOL) in cancer patients including the detection and management of emotional distress and sexual dysfunction in routine clinical practice. Initially funded by the NCRI Compass Collaborative she developed guidelines for oncologists to manage emotional distress in clinics and has explored health professionals’ attitudes to the use of antidepressants in clinical care. To facilitate behaviour change in clinicians Trish was involved in a training programme for Doctors to interpret and incorporate patient reported quality of life (QOL) data into routine consultations. More recently she has completed a systematic review to aid the selection of measures to report adverse events in radical prostate patients in the eRAPID radiotherapy project. She has also worked with staff and patients and used the cognitive interview process and consensus methodology (Delphi) to explore and enable the selection and understanding of questionnaire items.


Holch, P., Absolom, K. L., Henry, A. M., Walker, K., Gibson, A., Hudson, E., Rogers, Z., Holmes, M., Peacock, R., Pini, S., Gilbert, A., Davidson, S., Routledge, J., Murphy, A., Franks, K., Hulme, C., Hewison, J., Morris, C., McParland, L., Brown, J., Velikova, G. (2023). Online Symptom Monitoring During Pelvic Radiation Therapy: Randomized Pilot Trial of the eRAPID Intervention. International journal of radiation oncology, biology, physics, 115(3), 664–676. https://doi.org/10.1016/j.ijrobp.2022.09.078 https://www.redjournal.org/article/S0360-3016(22)03416-2/fulltext

King, L., Matthews, S., Foster, C., Starkings, R., Holch, P., Absolom, K., Archer, S., & of the British Psychosocial Oncology Society Executive Committee (2022). ‘A fascinating time to be involved with research’ exploring the impact of COVID-19 on postgraduate psycho-oncology researchers. Psycho-oncology, 31(4), 671–675. https://doi.org/10.1002/pon.5885

van Oppen, J. D., Alshibani, A., Coats, T. J., Graham, B., Holch, P., Lalseta, J., Mackintosh, N., Richardson, V., Riley, P., Valderas, J. M., & Conroy, S. P. (2022). A systematic review and recommendations for prom instruments for older people with frailty in emergency care. Journal of patient-reported outcomes, 6(1), 30. https://doi.org/10.1186/s41687-022-00438-x

Fielden, N., & Holch, P. (2022). ‘Exploring the Influence of Social Media Influencers on Intention to Attend Cervical Screening in the UK: Utilising the Theory of Planned Behaviour.’ Cancer Control. https://doi.org/10.1177/10732748221079480

Velikova, G, Absolom, K, Hewision, J, Holch, P, Avery , K, et al., (2022) Electronic self-reporting of adverse events for patients undergoing cancer treatment: the eRAPID research programme including two RCTs. NIHR Programme Grants for Applied Research: 10 (01)  https://doi.org/10.3310/FDDE8516

Pompili C; Rogers Z; Absolom K; Holch P; Clayton B; Callister M; Robson J; Brunelli A; Franks K; Velikova G (2021) Quality of life after VATS lung resection and SABR for early-stage non-small cell lung cancer: A longitudinal study. Lung Cancer, 162 pp. 71-78.

Absolom K; Warrington L; Hudson E; Hewison J; Holch P; Dawkins B; Hulme C; Brown J; Velikova G (2021) Reply to H. Shojima et al. Journal of Clinical Oncology, 39 (23), pp. 2633-2634.

Andrzejowski P, Holch P, Giannoudis PV. Measuring functional outcomes in major trauma: can we do better? Eur J Trauma Emerg Surg. 2021 Jun 26. doi: 10.1007/s00068-021-01720-1. Epub ahead of print. PMID: 34175971. Impact factor 2.139

Absolom K, Warrington L, Hudson E, Hewison J, Morris C, Holch P, Carter R, Gibson A, Holmes M, Clayton B, Rogers Z, McParland L, Conner M, Glidewell L, Woroncow B, Dawkins B, Dickinson S, Hulme C, Brown J, Velikova G. Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy. J Clin Oncol. 2021 Jan 8:JCO2002015. doi: 10.1200/JCO.20.02015. Epub ahead of print. PMID: 33417506. Impact factor 44.544

Holch P, Marwood JR. EHealth Literacy in UK Teenagers and Young Adults: Exploration of Predictors and Factor Structure of the eHealth Literacy Scale (eHEALS). JMIR Form Res. 2020 Sep 8;4(9):e14450. doi: 10.2196/14450. PMID: 32897230; PMCID: PMC7509638.

Archer S; Holch P; Armes J; Calman L; Foster C; Gelcich S; MacLennan SJ; Absolom K (2020), “No turning back” Psycho‐oncology in the time of COVID‐19: Insights from a survey of UK professionals https://doi.org/10.1002/pon.5486 Impact Factor 3.380

Pompili C, Holch P, Rogers Z, Absolom K, Clayton B, Franks K, Bekker H, Velikova G. Patients’ confidence in treatment decisions for early stage non-small cell lung cancer (NSCLC). Health Qual Life Outcomes. 2020 Jul 18;18(1):237. doi: 10.1186/s12955-020-01496-9. PMID: 32682425; PMCID: PMC7368734. Impact Factor 2.278

Pompili C, Boele F, Absolom K, Holch P, Clayton B, Smyllie E, Franks K, Velikova G. Patients’ views of routine quality of life assessment following a diagnosis of early-stage non-small cell lung cancer. Interact Cardiovasc Thorac Surg. 2020 Sep 1;31(3):324-330. doi: 10.1093/icvts/ivaa123. PMID: 32830244. Impact Factor 1.112

Warrington L; Absolom K; Holch P; Gibson A; Clayton B; Valikova G (2019), Online tool for monitoring adverse events in patients with cancer during treatment (eRAPID): field testing in a clinical setting https://doi.org/10.1136/bmjopen-2018-025185

Holch, P, Wilson R, Bostock, J (2019) Patient involvement in PROMS—individual opportunity and strategic challenge. British Medical Journal Opinion. https://blogs.bmj.com/bmj/2019/07/23/patient-involvement-in-proms-individual-opportunity-and-strategic-challenge

Holch, P., Pini, S., Henry, A.M., Davidson, S., Routledge, J., Brown, J., Absolom, K., Gilbert, A., Franks, K., Hulme, C., Morris, C., Velikova, G. and eRAPID radiotherapy work group, #. (2018) eRAPID electronic patient self-Reporting of Adverse-events: Patient Information and aDvice: a pilot study protocol in pelvic radiotherapy. Pilot & Feasibility Studies, 4 (110) doi.org/10.1186/s40814-018-0304-6, 632 views.

Chauhan, M., Holch, P. and Holbourn, C. (2018) Assessing the information and support needs of radical prostate cancer patients and acceptability of a group-based treatment review: A questionnaire and qualitative interview study. Journal of Radiotherapy in Practice, June: 151-161

Holch, P., Warrington, L., Bamforth, L.C.A., Keding, A., Ziegler, L.E., Absolom, K., Hector, C., Harley, C., Johnson, O., Hall, G., Morris, C. and Velikova, G. (2017) Development of an integrated electronic platform for patient self-report and management of adverse events during cancer treatment. Annals of Oncology, 28 (9) 2305-2311. doi: 10.1093/annonc/mdx317.

Absolom, K., Holch, P., Warrington, L., Samy, F., Hulme, C., Hewison, J., Morris, C., Bamforth, L., Conner, M., Brown, J. and Velikova, G. (2017) Electronic patient self-Reporting of adverse-events: Patient information and advice (eRAPID): A randomised controlled trial in systemic cancer treatment. BMC Cancer, 17 (318) doi: 10.1186/s12885-017-3303-8.

Pompili, C., Franks, K.N., Brunelli, A., Hussain, Y.S., Holch, P., Callister, M.E., Robson, J.M., Papagiannopoulos, K. and Velikova, G. (2017) Patient reported outcomes following video assisted thoracoscopic (VATS) resection or stereotactic ablative body radiotherapy (SABR) for treatment of non-small cell lung cancer: protocol for an observational pilot study (LiLAC). Journal of Thoracic Disease, 9 (8) August, pp. 2703-2713

Mercicabebber, R., Rouette, J., Calvert, M., King, M.T., Mcleod, L., Holch, P., Palmer, M.J. and Brundage, M. (2017) Preliminary evidence on the uptake, use and benefits of the CONSORT-PRO extension. Quality of Life Research, February, pp. 1-11.

Warrington, L., Holch, P., Kenyon, L., Hector, C., Kozlowska, K., Kenny, A.M., Ziegler, L. and Velikova, G (2016) An audit of acute oncology services: patient experiences of admission procedures and staff utilisation of a new telephone triage system. Supportive Care in Cancer, 24 (12) December, pp. 5041-5048.

Holch, P., Warrington, L., Potrata, B., Ziegler, L., Hector, C., Keding, A., Harley, C., Absolom, K., Morris, C., Bamforth, L. and Velikova, G. (2016) Asking the right questions to get the right answers: Using cognitive interviews to review the acceptability, comprehension and clinical meaningfulness of patient self-report adverse event items in oncology patients. Acta Oncologica, VOL. 55, NO. 9-10, 1220–1226.doi.org/10.1080/0284186X.2016.1213878.

Holch, P., Henry, A.M., Davidson, S., Gilbert, A., Routledge, J., Shearsmith, L., Franks, K., Ingleson, E., Albutt, A. and Velikova, G. (2016) Acute and Late Adverse Events Associated with Radical Radiation Therapy Prostate Cancer Treatment: A Systematic Review of Clinician and Patient Toxicity Reporting in Randomized Controlled Trials. International Journal of Radiation Oncology Biology Physics, 97 (3), 495-510.  doi: 10.1016/j.ijrobp.2016.11.008.

Absolom, K., Holch, P., Woroncow, B., Wright, E.P. and Velikova, G. (2015) Beyond lip service and box ticking: how effective patient engagement is integral to the development and delivery of patient-reported outcomes. Quality of Life Research, 24 (5) May, pp. 1077-1085. Impact factor 2.392

Holch, P., Absolom, K.L., Pini, S., Hill, K.M., Liu, A., Sharpe, M., Richardson, A., Hosker, C. and Velikova, G. (2011) Oncology professionals’ views on the use of antidepressants in cancer patients: a qualitative interview study. BMJ supportive & palliative Care, 1 (3) December, pp. 301-305

Absolom, K., Holch, P., Pini, S., Hill, K., Liu, A., Sharpe, M., Richardson, A. and Velikova, G. (2011) The detection and management of emotional distress in cancer patients: The views of health-care professionals. Psycho-Oncology, 20 (6) June, pp. 601-608.

Rodgers, R.J., Holch, P. and Tallett, A.J. (2010) Behavioural satiety sequence (BSS): Separating wheat from chaff in the behavioural pharmacology of appetite. Pharmacology Biochemistry and Behavior, 97 (1) November, pp. 3-14. (Review, Journal

Boggiano, M.M., Chandler, P.C., Oswald, K.D., Rodgers, R.J., Blundell, J.E., Ishii, Y., Beattie, A.H., Holch, P., Allison, D.B., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Schoelch, C.,Joost, H.G.,Klaus, S.,ThöneBineke, C., Benoit, S.C., Seeley, R.J., BeckSickinger, A.G., Koglin, N., Raun, K., Madsen, K., Wulff, B.S., Stidsen, C.E., Birringer,M., Kreuzer, O.J., Deng, X.Y., Whitcomb, D.C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Ortmann, S., Castañeda, T.R. and TschP, M. (2005) PYY3-36 as an anti-obesity drug target. Obesity Reviews, 6 (4) November, pp. 307-322. (Review, Journal) Impact factor 8.483

Madill, A. and Holch, P. (2004) A range of memory possibilities: The challenge of the false memory debate for clinicians and researchers. Clinical Psychology & Psychotherapy, 11 (5), pp. 299-310. Impact factor 2.578

Tschop, M., Castañeda, T.R., Joost, H.G., ThöneReineke, C., Ortmann, S., Klaus, S., Hagan, M.M., Chandler, P.C., Oswald, K.D., Benoit, S.C., Seeley, R.J., Kinzig, K.P., Moran, T.H., Becksickinger, A.G., Koglin, N., Rodgers, R.J., Blundell, J.E., Ishii, Y., Beattie, A.H., Holch, P., Allison, D.B., Raun, K., Madsen, K., Wulff, B.S., Stidsen, C.E., Birringer, M., Kreuzer, O.J., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Deng, X.Y., Withcomb, D.C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Craney, S., Flora, D., Smiley, D. and Heiman, M.L. (2004) Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature, 8;430(6996). Impact factor 41.577


Absolom, K., Holch, P. and Amir, Z. (2017) Introduction to special section on digital technology and cancer survivorship. Journal of cancer survivorship: research and practice, 11(6):655-657. doi: 10.1007/s11764-017-0644-x


Guest lecturer on the MSc Psychological Approaches to Health (PATH) course IPS University of Leeds (2013 & 2014)

Tutor on the Research, Evaluation and Special Studies module of the year 1 MBChB course.

Trish has completed the University of Leeds Teaching Award (Level 1) in 2010

Student supervision

Joint supervision of MSc PATH (Psychological Approaches to Health) student Abigail Albutt ‘Individual-Based vs. Group-Based Psychoeducation Sessions for Breast Cancer Survivors Following Radiotherapy (RT): Impact on Health-Related Quality of Life and Self-Efficacy’ with Dr Pete Gardner IPS University of Leeds (2014)- distinction gained. Oral presentation at BPOS and BPOS student bursary

Joint supervision of Munisha Ghattaure (Radiotherapy practitioner) with Catherine Holborn ‘To identify and assess the needs of radical prostate cancer patients with a view to stratify for a group review’ Sheffield Hallam University MSc Radiotherapy and Oncology (ongoing)-

Joint supervision of Alan Needham (Senior Radiotherapy practitioner) with Dr David Owens LIHS University of Leeds ‘Barriers to referral for sexual function support for patients undergoing prostate radiotherapy’(ongoing)

Professional Activities

Executive committee member of British Psychosocial Oncology Society (BPOS)

Scientific committee member (BPOS 2014, ISOQOL 2013)

Task force member: ISOQOL Best Practices for PROs in Randomized Clinical Trials

Athena Swan local assessment group member


International Society for Quality of Life (ISOQOL)

Associate of the Higher Education Academy (HEA)

British Psychosocial Oncology Society (BPOS)

British Psychological Society (BPS)

BPS Division of Health Psychology

BPS Oncology and Palliative care faculty (SiGOPAC)